How to connect OpenAI Responses and Zendesk
Create a New Scenario to Connect OpenAI Responses and Zendesk
In the workspace, click the “Create New Scenario” button.

Add the First Step
Add the first node – a trigger that will initiate the scenario when it receives the required event. Triggers can be scheduled, called by a OpenAI Responses, triggered by another scenario, or executed manually (for testing purposes). In most cases, OpenAI Responses or Zendesk will be your first step. To do this, click "Choose an app," find OpenAI Responses or Zendesk, and select the appropriate trigger to start the scenario.

Add the OpenAI Responses Node
Select the OpenAI Responses node from the app selection panel on the right.

OpenAI Responses
Configure the OpenAI Responses
Click on the OpenAI Responses node to configure it. You can modify the OpenAI Responses URL and choose between DEV and PROD versions. You can also copy it for use in further automations.
Add the Zendesk Node
Next, click the plus (+) icon on the OpenAI Responses node, select Zendesk from the list of available apps, and choose the action you need from the list of nodes within Zendesk.

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Authenticate Zendesk
Now, click the Zendesk node and select the connection option. This can be an OAuth2 connection or an API key, which you can obtain in your Zendesk settings. Authentication allows you to use Zendesk through Latenode.
Configure the OpenAI Responses and Zendesk Nodes
Next, configure the nodes by filling in the required parameters according to your logic. Fields marked with a red asterisk (*) are mandatory.
Set Up the OpenAI Responses and Zendesk Integration
Use various Latenode nodes to transform data and enhance your integration:
- Branching: Create multiple branches within the scenario to handle complex logic.
- Merging: Combine different node branches into one, passing data through it.
- Plug n Play Nodes: Use nodes that don’t require account credentials.
- Ask AI: Use the GPT-powered option to add AI capabilities to any node.
- Wait: Set waiting times, either for intervals or until specific dates.
- Sub-scenarios (Nodules): Create sub-scenarios that are encapsulated in a single node.
- Iteration: Process arrays of data when needed.
- Code: Write custom code or ask our AI assistant to do it for you.

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AI Anthropic Claude 3
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Trigger on Webhook
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Save and Activate the Scenario
After configuring OpenAI Responses, Zendesk, and any additional nodes, don’t forget to save the scenario and click "Deploy." Activating the scenario ensures it will run automatically whenever the trigger node receives input or a condition is met. By default, all newly created scenarios are deactivated.
Test the Scenario
Run the scenario by clicking “Run once” and triggering an event to check if the OpenAI Responses and Zendesk integration works as expected. Depending on your setup, data should flow between OpenAI Responses and Zendesk (or vice versa). Easily troubleshoot the scenario by reviewing the execution history to identify and fix any issues.
Most powerful ways to connect OpenAI Responses and Zendesk
Zendesk + OpenAI Responses + Slack: When a new ticket is created in Zendesk, OpenAI summarizes the ticket details, and then Slack posts the summary to a designated channel for quick team review.
Zendesk + OpenAI Responses + Google Sheets: When a ticket is updated in Zendesk, OpenAI analyzes the ticket's sentiment. The sentiment analysis results are then logged in Google Sheets for reporting purposes.
OpenAI Responses and Zendesk integration alternatives
About OpenAI Responses
Need AI-powered text generation? Use OpenAI Responses in Latenode to automate content creation, sentiment analysis, and data enrichment directly within your workflows. Streamline tasks like generating product descriptions or classifying customer feedback. Latenode lets you chain AI tasks with other services, adding logic and routing based on results – all without code.
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About Zendesk
Automate Zendesk ticket management within Latenode. Update tickets based on external events, route requests using AI, and sync data across platforms. Close the loop between support and other systems using visual flows, JavaScript, and webhooks—reducing manual work.
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FAQ OpenAI Responses and Zendesk
How can I connect my OpenAI Responses account to Zendesk using Latenode?
To connect your OpenAI Responses account to Zendesk on Latenode, follow these steps:
- Sign in to your Latenode account.
- Navigate to the integrations section.
- Select OpenAI Responses and click on "Connect".
- Authenticate your OpenAI Responses and Zendesk accounts by providing the necessary permissions.
- Once connected, you can create workflows using both apps.
Can I automatically summarize Zendesk tickets with OpenAI?
Yes, you can! Latenode lets you trigger OpenAI Responses with new Zendesk tickets, automatically summarizing the issue. This saves agents time and improves response efficiency.
What types of tasks can I perform by integrating OpenAI Responses with Zendesk?
Integrating OpenAI Responses with Zendesk allows you to perform various tasks, including:
- Automatically drafting responses to Zendesk tickets using OpenAI.
- Analyzing customer sentiment from Zendesk tickets using AI models.
- Generating knowledge base articles from resolved Zendesk tickets.
- Tagging Zendesk tickets based on the content analyzed by OpenAI.
- Creating AI-powered chatbots for Zendesk to handle common queries.
How secure is my OpenAI Responses data when using Latenode integrations?
Latenode employs enterprise-grade security measures, including encryption and access controls, ensuring your data remains protected at all times.
Are there any limitations to the OpenAI Responses and Zendesk integration on Latenode?
While the integration is powerful, there are certain limitations to be aware of:
- Rate limits imposed by OpenAI and Zendesk APIs may affect performance.
- Complex workflows might require advanced Latenode plan features.
- Custom prompt engineering might be necessary for optimal AI response quality.