How to connect OpenAI GPT Assistants and Zendesk
Create a New Scenario to Connect OpenAI GPT Assistants and Zendesk
In the workspace, click the “Create New Scenario” button.

Add the First Step
Add the first node – a trigger that will initiate the scenario when it receives the required event. Triggers can be scheduled, called by a OpenAI GPT Assistants, triggered by another scenario, or executed manually (for testing purposes). In most cases, OpenAI GPT Assistants or Zendesk will be your first step. To do this, click "Choose an app," find OpenAI GPT Assistants or Zendesk, and select the appropriate trigger to start the scenario.

Add the OpenAI GPT Assistants Node
Select the OpenAI GPT Assistants node from the app selection panel on the right.

OpenAI GPT Assistants
Configure the OpenAI GPT Assistants
Click on the OpenAI GPT Assistants node to configure it. You can modify the OpenAI GPT Assistants URL and choose between DEV and PROD versions. You can also copy it for use in further automations.
Add the Zendesk Node
Next, click the plus (+) icon on the OpenAI GPT Assistants node, select Zendesk from the list of available apps, and choose the action you need from the list of nodes within Zendesk.

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Authenticate Zendesk
Now, click the Zendesk node and select the connection option. This can be an OAuth2 connection or an API key, which you can obtain in your Zendesk settings. Authentication allows you to use Zendesk through Latenode.
Configure the OpenAI GPT Assistants and Zendesk Nodes
Next, configure the nodes by filling in the required parameters according to your logic. Fields marked with a red asterisk (*) are mandatory.
Set Up the OpenAI GPT Assistants and Zendesk Integration
Use various Latenode nodes to transform data and enhance your integration:
- Branching: Create multiple branches within the scenario to handle complex logic.
- Merging: Combine different node branches into one, passing data through it.
- Plug n Play Nodes: Use nodes that don’t require account credentials.
- Ask AI: Use the GPT-powered option to add AI capabilities to any node.
- Wait: Set waiting times, either for intervals or until specific dates.
- Sub-scenarios (Nodules): Create sub-scenarios that are encapsulated in a single node.
- Iteration: Process arrays of data when needed.
- Code: Write custom code or ask our AI assistant to do it for you.

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AI Anthropic Claude 3
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Trigger on Webhook
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Save and Activate the Scenario
After configuring OpenAI GPT Assistants, Zendesk, and any additional nodes, don’t forget to save the scenario and click "Deploy." Activating the scenario ensures it will run automatically whenever the trigger node receives input or a condition is met. By default, all newly created scenarios are deactivated.
Test the Scenario
Run the scenario by clicking “Run once” and triggering an event to check if the OpenAI GPT Assistants and Zendesk integration works as expected. Depending on your setup, data should flow between OpenAI GPT Assistants and Zendesk (or vice versa). Easily troubleshoot the scenario by reviewing the execution history to identify and fix any issues.
Most powerful ways to connect OpenAI GPT Assistants and Zendesk
Zendesk + OpenAI GPT Assistants + Slack: When a new ticket is created in Zendesk, the ticket details are sent to an OpenAI GPT Assistant. The assistant analyzes the ticket and suggests a solution. This suggested solution is then posted to a designated Slack channel for review.
Zendesk + OpenAI GPT Assistants + Google Sheets: When a ticket is updated in Zendesk, the updated ticket information is sent to an OpenAI GPT Assistant, which summarizes the ticket. This summary, along with the ticket ID, is then added as a new row in a Google Sheet for tracking and analysis.
OpenAI GPT Assistants and Zendesk integration alternatives
About OpenAI GPT Assistants
Use OpenAI GPT Assistants within Latenode to automate complex tasks like customer support or content creation. Configure Assistants with prompts and integrate them into broader workflows. Chain them with file parsing, webhooks, or database updates for scalable, automated solutions. Benefit from Latenode's no-code flexibility and affordable execution-based pricing.
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About Zendesk
Automate Zendesk ticket management within Latenode. Update tickets based on external events, route requests using AI, and sync data across platforms. Close the loop between support and other systems using visual flows, JavaScript, and webhooks—reducing manual work.
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FAQ OpenAI GPT Assistants and Zendesk
How can I connect my OpenAI GPT Assistants account to Zendesk using Latenode?
To connect your OpenAI GPT Assistants account to Zendesk on Latenode, follow these steps:
- Sign in to your Latenode account.
- Navigate to the integrations section.
- Select OpenAI GPT Assistants and click on "Connect".
- Authenticate your OpenAI GPT Assistants and Zendesk accounts by providing the necessary permissions.
- Once connected, you can create workflows using both apps.
Can I automatically answer Zendesk tickets using GPT Assistants?
Yes, you can! Latenode’s visual editor makes it easy to route new Zendesk tickets to OpenAI GPT Assistants for intelligent responses, saving time and improving support efficiency.
What types of tasks can I perform by integrating OpenAI GPT Assistants with Zendesk?
Integrating OpenAI GPT Assistants with Zendesk allows you to perform various tasks, including:
- Automatically summarizing Zendesk tickets using AI.
- Generating suggested responses for support agents.
- Classifying tickets by topic and sentiment.
- Updating Zendesk ticket properties based on AI analysis.
- Creating new Zendesk tickets from OpenAI GPT Assistants conversations.
How to use custom prompts in my OpenAI GPT Assistants + Zendesk flows?
Latenode lets you inject custom prompts into your workflows, ensuring OpenAI GPT Assistants responds precisely to your specific Zendesk data and scenarios.
Are there any limitations to the OpenAI GPT Assistants and Zendesk integration on Latenode?
While the integration is powerful, there are certain limitations to be aware of:
- Rate limits of the OpenAI GPT Assistants and Zendesk APIs may affect performance.
- Complex workflows with extensive data processing may require careful optimization.
- Access to certain advanced OpenAI GPT Assistants features depends on your OpenAI plan.